Dapagliflozin-3-O-β-D-Glucuronide - CAS 1351438-75-9

Dapagliflozin-3-O-β-D-glucuronide is a metabolite of dapagliflozin . Dapagliflozin is a first generation selective sodium glucose cotransporter (SGLT) 2 inhibitor that blocks glucose transport.[1] Dapagliflozin is metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A9 to dapagliflozin-3-O-β-D-glucuronide, which is 2,600-fold less potent than the parent compound with regard to SGLT2 inhibition.[2]

Others, Endogenous Metabolite

Others, Metabolism

1351354

C27H33ClO12

585

O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O)C3=CC(CC4=CC=C(OCC)C=C4)=C(Cl)C=C3

-20°C

Ice Packs

Small Compound