Daphnetin - CAS 486-35-1

Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-inflammatory activities.

PKC, ROS, PKA, AMPK, Autophagy, EGFR, mTOR, Parasite, Reactive Oxygen Species, Apoptosis, PARP, Caspase, Bcl-2 Family, Akt

PI3K/Akt/mTOR signaling, NF-κB, Proteases/Proteasome, Tyrosine Kinase/Adaptors, Microbiology/Virology, Immunology/Inflammation, Autophagy, Chromatin/Epigenetic, Metabolism, Cytoskeletal Signaling, JAK/STAT signaling, DNA Damage/DNA Repair, Apoptosis, Angiogenesis

450

0.9982

C9H6O4

178.14

Oc1ccc2ccc(=O)oc2c1O

-20°C

Ice Packs

Natural Product