Dapivirine HCl - CAS 244768-47-6

Dapivirine HCl is the salt form of Dapivirine, also known as TMC120, a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. The HIV-1 replication inhibitor dapivirine (DPV) is one of the most promising drug candidates being used in topical microbicide products for prevention of HIV-1 sexual transmission.

Apoptosis, HIV Protease, Autophagy, Reverse Transcriptase, Others

Autophagy, Proteases/Proteasome, Others, Apoptosis, Microbiology/Virology

244715

C20H20ClN5

365.86

N(C1=C(C)C=C(C)C=C1C)C2=NC(NC3=CC=C(C#N)C=C3)=NC=C2.Cl

-20°C

Ice Packs

Small Compound