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Dapolsertib - CAS 1616359-00-2

Dapolsertib - CAS 1616359-00-2

MF-0045556-01

$57.84 USD
$57.84 USD
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Product Details

  • Bioactivity

    Dapolsertib (SEL24-B489) is an orally bioavailable and potent PIM and FLT3-ITD inhibitor, inhibiting PIM1, PIM2, and PIM3, decreasing PIM substrate phosphorylation, and inducing dose-dependent apoptosis in leukemia cells.

  • Target

    Pim, FLT, Apoptosis

  • Related Pathways

    Tyrosine Kinase/Adaptors, JAK/STAT signaling, Apoptosis, Angiogenesis, Chromatin/Epigenetic

  • CAS Number

    1616359-00-2

  • Purity

    0.9961

  • Molecular Formula

    C15H18Br2N4O2

  • Molecular Weight

    446.14

  • SMILES

    O=N(=O)C=1C(Br)=C(Br)C=C2C1N=C(N2C(C)C)C3CCNCC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound