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Molfinity

DAPT - CAS 208255-80-5

DAPT - CAS 208255-80-5

SKU:MF-0013178-01

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  • Bioactivity

    DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces cell differentiation, autophagy and apoptosis.

  • Target

    Beta Amyloid, Apoptosis, Autophagy, Gamma-secretase

  • Related Pathways

    Neuroscience, Stem Cells, Apoptosis, Autophagy, Proteases/Proteasome

  • CAS Number

    208170

  • Purity

    0.9981

  • Molecular Formula

    C23H26F2N2O4

  • Molecular Weight

    432.46

  • SMILES

    C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@H](C(=O)OC(C)(C)C)c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound