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DAPT - CAS 208255-80-5
DAPT - CAS 208255-80-5
SKU:MF-0013178-01
Regular price
$35.41 USD
Regular price
Sale price
$35.41 USD
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Product Details
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Bioactivity
DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces cell differentiation, autophagy and apoptosis.
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Target
Beta Amyloid, Apoptosis, Autophagy, Gamma-secretase
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Related Pathways
Neuroscience, Stem Cells, Apoptosis, Autophagy, Proteases/Proteasome
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CAS Number
208170
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Purity
0.9981
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Molecular Formula
C23H26F2N2O4
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Molecular Weight
432.46
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SMILES
C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@H](C(=O)OC(C)(C)C)c1ccccc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound