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Molfinity

Darizmetinib - CAS 2369583-33-3

Darizmetinib - CAS 2369583-33-3

MF-0095322-01

$59.34 USD
$59.34 USD
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Product Details

  • Bioactivity

    Darizmetinib (HRX215, HRX-0215) is an MKK4 inhibitor. Inhibition of MKK4 leads to enhancement of the MKK7 and JNK1 signaling pathways, thereby activating the transcription factors ATF2 and ELK1, promoting cell proliferation and liver regeneration.

  • Target

    P38 MAPK, Antiviral, NF-κB, MDM-2/p53, JNK, MAPK

  • Related Pathways

    NF-κB, Immunology/Inflammation, MAPK, Apoptosis

  • CAS Number

    2369547

  • Purity

    0.9957

  • Molecular Formula

    C21H17F2N5O3S

  • Molecular Weight

    457.45

  • SMILES

    O=C(C1=NNC2=NC=C(C=C21)C=3C=CN=CC3)C4=CC=C(F)C(NS(=O)(=O)CCC)=C4F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound