Dasabuvir - CAS 1132935-63-7

Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase. Upon administration and intracellular uptake, dasabuvir binds HCV NS5B polymerase, blocking viral RNA synthesis and replication. The HCV NS5B protein is essential for the replication of the HCV RNA genome.

HCV Protease, DNA/RNA Synthesis

Microbiology/Virology, DNA Damage/DNA Repair, Proteases/Proteasome, Cell Cycle/Checkpoint

1132865

0.9962

C26H27N3O5S

493.57

COc1c(cc(cc1C(C)(C)C)-n1ccc(=O)[nH]c1=O)-c1ccc2cc(NS(C)(=O)=O)ccc2c1

-20°C

Ice Packs

Small Compound