DB-766 - CAS 423165-22-4

DB-766 is a potential chemotherapeutic candidate for Chagas' disease treatment. DB-766 exhibits strong trypanocidal activity and excellent selectivity for bloodstream trypomastigotes and intracellular amastigotes (Y strain), giving IC (50) s of 60 and 25 nM, respectively. The trypanocidal efficacy of DB766, suggesting that this AIA may represent a new lead compound candidate to Chagas.

Others, Parasite

Microbiology/Virology, Others

423139

C34H34N6O3

574.67

O(C(C)C)C1=C(C=CC(NC(=N)C2=CC=CC=N2)=C1)C=3OC(=CC3)C4=C(OC(C)C)C=C(NC(=N)C5=CC=CC=N5)C=C4

-20°C

Ice Packs

Small Compound