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DB21, Galectin-1 Antagonist - CAS 1623027-80-4
DB21, Galectin-1 Antagonist - CAS 1623027-80-4
SKU:MF-0159733-01
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Product Details
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Bioactivity
DB21, Galectin-1 Antagonist, is a peptidomimetic conjugated with dibenzofuran, serving as an allosteric inhibitor of galectin-1 (GAL1) interactions with glycans on cell surfaces. This compound enhances the inhibition of angiogenesis and tumor growth in melanoma, lung adenocarcinoma, and ovarian cancer models [1].
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Target
Galectin
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Related Pathways
Immunology/Inflammation
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CAS Number
1623027-80-4
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Molecular Formula
C83H136N18O19
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Molecular Weight
1690.08
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SMILES
C(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CO)N)=O)C(C)C)=O)CCC(N)=O)=O)CCC)=O)CCCCN)=O)CC(C)C)=O)C1=C2C(C=3C(O2)=C(CCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CC(N)=O)=O)CC(C)C)=O)CCCCN)=O)[C@@H](C)C)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C=CC3)=CC=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide