DBCO-NHS ester 3 - CAS 1393350-27-0

DBCO-NHS ester 3 (Compound 12) is a cleavable linker utilized in the synthesis of antibody-drug conjugate (ADC) . It is a derivative of Dibenzylcyclooctyne (DBCO) resulting from the activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC) [1][2].

ADC Linker

Antibody-drug Conjugate/ADC Related

1393323

C24H20N2O5

416.43

O=C(ON1C(=O)CCC1=O)CCCC(=O)N2C=3C=CC=CC3C#CC=4C=CC=CC4C2

-20°C

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