DBCO- (PEG2-VC-PAB-MMAE) 2 - CAS 2259318-55-1

DBCO- (PEG2-VC-PAB-MMAE) 2 consists of Monomethyl auristatin E (MMAE), a potent tubulin inhibitor and toxin payload in antibody-drug conjugate [1], conjugated to the cleavable linker DBCO- (PEG2-VC-PAB) 2, serving as the cytotoxic component in this formulation.

Drug-Linker Conjugates for ADC

Antibody-drug Conjugate/ADC Related

2259262

C149H224N22O32

2835.5

C(CCC(N(CCOCCOCCC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(N([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(=O)N2[C@]([C@@H]([C@H](C(N[C@@H]([C@@H](O)C3=CC=CC=C3)C)=O)C)OC)(CCC2)[H])OC)[C@H](CC)C)C)=O)C(C)C)=O)C(C)C)C)=O)C=C1)=O)CCCNC(N)=O)=O)C(C)C)=O)CCOCCOCCC(N[C@H](C(N[C@H](C(NC4=CC=C(COC(N([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(=O)N5[C@]([C@@H]([C@H](C(N[C@@H]([C@@H](O)C6=CC=CC=C6)C)=O)C)OC)(CCC5)[H])OC)[C@H](CC)C)C)=O)C(C)C)=O)C(C)C)C)=O)C=C4)=O)CCCNC(N)=O)=O)C(C)C)=O)=O)(=O)N7C=8C(C#CC=9C(C7)=CC=CC9)=CC=CC8

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