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DBCO-PEG3-VC-Exatecan - CAS 2754384-70-6
DBCO-PEG3-VC-Exatecan - CAS 2754384-70-6
SKU:MF-0110465-01
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Product Details
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Bioactivity
DBCO-PEG3-VC-Exatecan (compound 25) is a Drug-Linker Conjugate for ADC (ADC Drug-Linker Conjugate), consisting of the ADC linker (DBCO-PEG3-VC) coupled with the DNA topoisomerase I (topoisomeraseI) inhibitor Exatecan. This conjugate is utilized in the development of antibody-drug conjugates for targeted cancer therapy.
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Target
Drug-Linker Conjugates for ADC, Topoisomerase
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Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
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CAS Number
2754308
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Molecular Formula
C71H79FN10O15
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Molecular Weight
1331.44
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SMILES
N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCOCCOCCOCCNC(CCC(=O)N2C=3C(C#CC=4C(C2)=CC=CC4)=CC=CC3)=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@H]5C6=C7C(C=8N(C7)C(=O)C9=C(C8)[C@](CC)(O)C(=O)OC9)=NC=%10C6=C(CC5)C(C)=C(F)C%10
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound