DBCO-PEG4-Val-Ala-PAB-PNP - CAS 2348405-93-4

DBCO-PEG4-Val-Ala-PAB-PNP is a cleavable ADC linker. The Val-Ala dipeptide sequence can be cleaved by cathepsin B. The DBCO group is typically utilized in click chemistry reactions. The PEG spacer enhances the compound's solubility in water. PNP serves as an effective leaving group.

ADC Linker

Antibody-drug Conjugate/ADC Related

2348405-93-4

C52H60N6O14

993.065

C(CCC(NCCOCCOCCOCCOCCC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(OC2=CC=C(N(=O)=O)C=C2)=O)C=C1)=O)C)=O)[C@H](C)C)=O)=O)(=O)N3C=4C(C#CC=5C(C3)=CC=CC5)=CC=CC4

-20°C

Ice Packs

Inhibitors & Agonists