Dbet57 - CAS 1883863-52-2

DBET57 is heterobifunctional degrader of BRD4 based on the PROTAC technology, exhibits significant degradation of BRD4BD1 with a DC50/5h of 500 nM , and inactive on BRD4BD2

Apoptosis, Epigenetic Reader Domain, PROTACs

PROTAC, Chromatin/Epigenetic, Apoptosis

1883809

0.9952

C34H31ClN8O5S

699.18

CC=1C2=C(N3C([C@H](CC(NCCNC4=C5C(C(=O)N(C5=O)C6C(=O)NC(=O)CC6)=CC=C4)=O)N=C2C7=CC=C(Cl)C=C7)=NN=C3C)SC1C

-20°C

Ice Packs

PROTAC