DBRD9-A - CAS 2170679-42-0

Potent BRD9 degrader. Selectively binds BRD9 and elicits near complete degradation of BRD9 at nanomolar concentrations. Inhibits growth of synovial sarcoma cells in vitro and tumor progression in a synovial sarcoma xenograft mouse model.

Others, PROTACs, Epigenetic Reader Domain

PROTAC, Chromatin/Epigenetic, Others

2170637

C42H49N7O8

779.88

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCCCCCNC(CN(CC4=C(OC)C=C(C=C4OC)C=5C=6C(C(=O)N(C)C5)=CN=CC6)C)=O

-20°C

Ice Packs

Small Compound