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Molfinity

DC-LC3in-D5 - CAS 2868312-73-4

DC-LC3in-D5 - CAS 2868312-73-4

MF-0094769-01

$106.25 USD
$106.25 USD
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Product Details

  • Bioactivity

    DC-LC3in-D5 is a potent and selective covalent inhibitor of LC3A/B that disrupts autophagy by covalently binding to Lys49 on LC3B (IC50 = 200 nM), resulting in impaired LC3B lipidation, accumulation of the autophagy substrate p62, and a significant reduction in the formation of autophagosome vesicles.

  • Target

    P62, Autophagy, ATG

  • Related Pathways

    Autophagy

  • CAS Number

    2868235

  • Purity

    0.9979

  • Molecular Formula

    C19H22Cl2N2O3

  • Molecular Weight

    397.3

  • SMILES

    O=C1C(=CNCCN2CCOCC2)C(=O)CC(C=3C=CC=C(Cl)C3Cl)C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound