DC-SX029 - CAS 300713-88-6

DC-SX029 is a potent inhibitor of SNX10 protein-protein interaction (PPI) with an estimated K D constant of approximately 0.935 μM as measured by surface plasmon resonance (SPR) . It blocks the SNX10-PIKfyve interaction, leading to decreased TBK1/c-Rel signaling activation, without affecting SNX10 protein levels. DC-SX029 shows potential for inflammatory bowel disease (IBD) research [1].

PI3K, IκB/IKK, NF-κB

PI3K/Akt/mTOR signaling, NF-κB

300713-88-6

C14H17F3N2O6S

398.36

S(NCC(CCC(O)=O)C(F)(F)F)(=O)(=O)C1=CC=C(NC(OC)=O)C=C1

-20°C

Ice Packs

Small Compound