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DC0-NH2 - CAS 615538-51-7
DC0-NH2 - CAS 615538-51-7
SKU:MF-0022053-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
The cytotoxicity of DC0-NH2 is 1000 times that of commonly used anti-cancer drugs (such as doxorubicin) . It is the effect part of ADC. It is a simplified simulation of DC1 and has better stability. DC0-NH2 can bind to the small groove of DNA, and then adenine residue is alkylated by its propabenzindole (CBI) component.
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Target
ADC Cytotoxin
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Related Pathways
Antibody-drug Conjugate/ADC Related
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CAS Number
615480
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Molecular Formula
C31H24ClN5O3
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Molecular Weight
550.01
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SMILES
Nc1ccc2[nH]c(cc2c1)C(=O)Nc1ccc2[nH]c(cc2c1)C(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound