DC41SMe - CAS 1354787-71-5

DC41SMe is a DC1 derivative that is cytotoxic to Ramos, Namalwa and HL60 / s with IC50s ranging from 18-25 pM. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylation molecules, used for targeted treatment of cancer.

ADC Cytotoxin

Antibody-drug Conjugate/ADC Related

1354711

C38H36ClN5O4S2

726.31

C(Cl)[C@H]1C2=C(N(C(=O)C=3NC=4C(C3)=CC(NC(=O)C=5NC=6C(C5)=CC(NC(CCC(SSC)(C)C)=O)=CC6)=CC4)C1)C=C(O)C=7C2=CC=CC7

-20°C

Ice Packs

Small Compound