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DC4SMe - CAS 615538-47-1
DC4SMe - CAS 615538-47-1
SKU:MF-0022062-01
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Product Details
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Bioactivity
The IC50s of DC4SMe on Ramos, Namalwa and HL60 / s cancer cells were 1.9 nM, 2.9 nM and 1.8 nM, respectively. DC4SMe can be used for targeted therapy of tumors. DC4SMe is a phosphate prodrug of the cytotoxic DNA alkylating agent DC4 and can be used in the synthesis of antibody-drug conjugates (ADC) .
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Target
ADC Cytotoxin
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Related Pathways
Antibody-drug Conjugate/ADC Related
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CAS Number
615490
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Molecular Formula
C35H31ClN5O7PS2
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Molecular Weight
764.21
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SMILES
C(Cl)[C@H]1C2=C(N(C(=O)C3=CC=4C(N3)=CC=C(NC(=O)C5=CC=6C(N5)=CC=C(NC(CCSSC)=O)C6)C4)C1)C=C(OP(=O)(O)O)C=7C2=CC=CC7
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound