DCB-3503 - CAS 87302-58-7

Tylophorine analog DCB-3503 is a potential anticancer and immunosuppressive agent. DCB-3503 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. DCB-3503 allosterically regulates the ATPase and chaperone activities of HSC70 by promoting ATP hydrolysis in the presence of specific RNA binding motifs (AUUUA) of cyclin D1 mRNA.

Others, HSP, CDK

Metabolism, Cytoskeletal Signaling, Cell Cycle/Checkpoint, Others

87302-58-7

C24H27NO5

409.47

O[C@H]1C=2C(=C3C(=C4C2C=C(OC)C(OC)=C4)C=C(OC)C(OC)=C3)CN5[C@]1(CCC5)[H]

-20°C

Ice Packs

Small Compound