DCBP-1 - CAS 2484739-25-3

DCBP-1 is a chemical degrader of p300/CBP. dCBP-1 hijacks the E3 ubiquitin ligase CRBN for selective degradation of p300/CBP. Degradation of p300/CBP by dCBP-1 leads to effective multiple myeloma cell killing.

PROTACs, Epigenetic Reader Domain

PROTAC, Chromatin/Epigenetic

2484711

0.9912

C51H63F2N11O10

1028.11

C(NC)(=O)N1CC=2C(=NN(C2CC1)C3CCN(C(CCOCCOCCOCCOCCNC=4C=C5C(=CC4)C(=O)N(C5=O)C6C(=O)NC(=O)CC6)=O)CC3)N7C=8C(=CC(=C(C(F)F)C8)C9=CN(C)N=C9)CCC7

-20°C

Ice Packs

PROTAC