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DCLK1-IN-1 - CAS 2222635-15-4

DCLK1-IN-1 - CAS 2222635-15-4

MF-0018851-01

$134.69 USD
$134.69 USD
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Product Details

  • Bioactivity

    DCLK1-IN-1 is a selective, in vivo compatible chemical probe of the kinase domain of doublecortin-like kinase 1 (DCLK1) and a highly selective DCLK1/2 inhibitor with IC50 values ​​of 9.5/57.2 nM (DCLK1) and 31/103 nM (DCLK2) by binding and kinase assays, respectively. It has low toxicity and is used to study DCLK1 biology and determine its role in cancer.

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    2222616

  • Purity

    >99.99%

  • Molecular Formula

    C26H28F3N7O2

  • Molecular Weight

    527.54

  • SMILES

    COc1cc(ccc1Nc1ncc2N(CC(F)(F)F)C(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound