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DCLK1-IN-5 - CAS 3028774-14-0

DCLK1-IN-5 - CAS 3028774-14-0

MF-0120529-01

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Product Details

  • Bioactivity

    DCLK1-IN-5 (Compound a24), with an IC 50 of 179.7 nM, acts as a DCLK1 inhibitor. It mitigates lipopolysaccharide-induced inflammation by blocking DCLK1-mediated IKKβ phosphorylation. Additionally, DCLK1-IN-5 offers protection to mice from lung injuries and sepsis caused by inflammation [1].

  • Target

    Serine Protease

  • Related Pathways

    Proteases/Proteasome

  • CAS Number

    3028774-14-0

  • Molecular Formula

    C26H32ClN7O3S2

  • Molecular Weight

    590.16

  • SMILES

    S(C(C)C)(=O)(=O)C1=C(NC2=NC(NC3=C(OC)C=C(NC(=S)N4CCN(C)CC4)C=C3)=NC=C2Cl)C=CC=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound