Molfinity

DD205-291 - CAS 3047066-15-6

SKU:MF-0110703-01

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Product Details

Bioactivity
DD205-291 is an orally active PROTAC HPK1 degrader with a DC50 of 5.3 nM. It inhibits SLP-76 phosphorylation and induces IL-2 and IFN-γ.
Target
PROTACs, GluR
Related Pathways
PROTAC, Neuroscience
CAS Number
3047045
Molecular Formula
C38H38ClF3N10O3
Molecular Weight
775.22
SMILES
O=C1NC(=O)CCN1C2=CC(=CC=C2Cl)C(=O)N3CCC(CC3)CC4CCN(C5=NC=C(C=C5)C6=NC7=C(N=C6)NC=C7C=8C=NN(C8)CC(F)(F)F)CC4
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
PROTAC