DDO-02267 - CAS 2919768-58-2

DDO-02267 is a selective lysine-targeted covalent inhibitor of ALKBH5, with an IC50 value of 0.49 μM. It increases levels of N6-methyladenosine (m6A) and targets the ALKBH5-AXL signaling axis. DDO-02267 serves as a probe for studying the biological function of mRNA demethylases.

ALK

Angiogenesis, Tyrosine Kinase/Adaptors

2919708

C18H12N2O7S

400.362

O=CC=1C=C(C=2C=CC=CC2C1O)S(=O)(=O)NC(=O)C3=NC=CC(=C3)C(=O)O

-20°C

Ice Packs

Small Compound