DDR1-IN-1 dihydrochloride - CAS 1780303-76-5

DDR1-IN-1 dihydrochloride is a selective and potent inhibitor of the DDR1 receptor tyrosine kinase, exhibiting an IC50 of 105 nM, and it demonstrates fourfold reduced potency against DDR2, with an IC50 of 413 nM.

Discoidin Domain Receptor (DDR), Others

Tyrosine Kinase/Adaptors, Others

1780222

C30H33Cl2F3N4O3

625.51

Cl.Cl.O=C(NC1=CC=C(C(OC2=CC=C3NC(=O)CC3=C2)=C1)C)C4=CC=C(C(=C4)C(F)(F)F)CN5CCN(CC)CC5

-20°C

Ice Packs

Small Compound