Deacylcortivazol - CAS 4906-84-7

Deacylcortivazol (DAC) is a potent glucocorticoid. When incubated with glucocorticoid-resistant mutants derived from the glucocorticoid-sensitive human leukemic cell line CEM-C7, DAC caused significant growth inhibition. The cytotoxicity of DAC at concentrations higher than necessary for glucocorticoid receptor saturation is not mediated by glucocorticoid receptors.

Others, Glucocorticoid Receptor

Endocrinology/Hormones, Others

4815

C30H36N2O4

488.62

C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@H]3O)[C@](C(CO)=O)(O)[C@H](C)C4)[H])(C=C(C)C1=CC5=C(C2)C=NN5C6=CC=CC=C6)[H])[H]

-20°C

Ice Packs

Small Compound