Decarbamoylmitomycin C - CAS 26909-37-5

Decarbamoylmitomycin C, an analog of Mitomycin C (MC), functions as a DNA alkylating agent. It is capable of activating chromatin relaxation by the ataxia-telangiectasia and Rad3-related protein (ATR) in a p53-independent manner.

MDM-2/p53, ATM/ATR

Apoptosis, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair

26867

C14H17N3O4

291.302

O(C)[C@]12N(C3=C([C@H]1CO)C(=O)C(N)=C(C)C3=O)C[C@]4([C@@]2(N4)[H])[H]

-20°C

Ice Packs

Small Compound