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Deethylindanomycin - CAS 106803-22-9

Deethylindanomycin - CAS 106803-22-9

SKU:MF-0049241

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  • Bioactivity

    Deethylindanomycin is a polyether antibiotic that has been found in S. setonii. It is active against a variety of Gram-positive bacteria, including various strains of S. aureus and Streptococcus, as well as one strain of S. pneumoniae (MICs = 4, 4, and 2 μg/ml, respectively) . It is also active against coccidia in vitro, inhibiting E. tenella development, but is inactive against E. tenella infection in chicks when administered at a dose of 200 μg/g in the diet. Deethylindanomycin acts as an ionophore in lipid bilayer membranes and is more selective for potassium ions than calcium, magnesium, and sodium ions. It induces histamine release from rodent mast cells and human basophils in vitro in a calcium-dependent manner.

  • Target

    Antibiotic, Antibacterial, Parasite, Others

  • Related Pathways

    Others, Microbiology/Virology

  • CAS Number

    106772

  • Molecular Formula

    C29H39NO4

  • Molecular Weight

    465.62

  • SMILES

    [H][C@@]12CCC[C@@]1([H])[C@]([H])(C(=O)c1ccc[nH]1)[C@@]([H])(\C=C\C=C(/CC)[C@]1([H])O[C@]([H])(CC[C@@H]1C)[C@@H](C)C(O)=O)C=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound