Molfinity

Defactinib - CAS 1073154-85-4

SKU:MF-0018552-01

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Size 1 mg 2 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg

Product Details

Bioactivity
Defactinib (VS-6063) is a second-generation inhibitor of FAK that inhibits FAK phosphorylation at the Tyr397 site. Defactinib has potential antitumor activity.
Target
FAK
Related Pathways
Cytoskeletal Signaling, Angiogenesis, Tyrosine Kinase/Adaptors
CAS Number
1073065
Purity
0.998
Molecular Formula
C20H21F3N8O3S
Molecular Weight
510.49
SMILES
CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound