Deferoxamine - CAS 70-51-9

Deferoxamine (Desferrioxamine B) is an iron chelator. Deferoxamine can be used to reduce the accumulation and deposition of iron in tissues. Deferoxamine can improve neurological dysfunction by inhibiting ferroptosis and neuroinflammation after traumatic brain injury. It has antioxidant, anti-proliferation and anti-tumor activities, and can induce the production of HIF-1α, apoptosis and autophagy in cancer cells. It can be used to treat acute iron toxicity and COVID-19 related diseases.

Antioxidant, Apoptosis, Reactive Oxygen Species, Akt, HIF/HIF Prolyl-Hydroxylase, Autophagy, ROS, HIF

NF-κB, Autophagy, Oxidation-Reduction, Immunology/Inflammation, PI3K/Akt/mTOR signaling, Angiogenesis, Chromatin/Epigenetic, Cytoskeletal Signaling, Metabolism, Apoptosis

70-51-9

0.9997

C25H48N6O8

560.68

O=C(NCCCCCN(O)C(=O)C)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN

-20°C

Ice Packs

Natural Product