Dehydroglyasperin D - CAS 517885-72-2

Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 human colorectal cancer cells through direct interaction with phosphatidylinositol 3-kinase; it also mediates suppression of both COX-2 expression and the MLK3 signalling pathway through direct binding and inhibition of MLK3. Dehydroglyasperin D shows strong ferric reducing activities and effectively scavenged DPPH, ABTS (+), and singlet oxygen radicals.

P38 MAPK, Reductase, Akt, Prostaglandin Receptor, GSK-3, JNK, COX, PI3K, DNA/RNA Synthesis, ROS

DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Endocrinology/Hormones, GPCR/G Protein, Metabolism, Neuroscience, Immunology/Inflammation, Cytoskeletal Signaling, Stem Cells, MAPK

517811

C22H24O5

368.42

O(C)C1=C2C(=CC(OC)=C1CC=C(C)C)OCC(=C2)C3=C(O)C=C(O)C=C3

-20°C

Ice Packs

Natural Product