Delanzomib - CAS 847499-27-8

Delanzomib (CEP-18770) is an orally active inhibitor of the chymotrypsin-like activity of proteasome (IC50: 3.8 nM) . It only marginally inhibits the tryptic and peptidylglutamyl activities of the proteosome.

NF-κB, Proteasome, Apoptosis

Proteases/Proteasome, Apoptosis, Ubiquitination, NF-κB

847464

0.9946

C21H28BN3O5

413.28

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)c1cccc(n1)-c1ccccc1)[C@@H](C)O)B(O)O

-20°C

Ice Packs

Small Compound