Delphinidin chloride - CAS 528-53-0

Delphinidin chloride, a natural plant pigment found in berries and red wine, is a precursor of certain anthocyanins. Delphinidin chloride induces the release of nitric oxide from the vascular endothelium, resulting in vascular relaxation. At the dose of 1-40 μM, epithelial growth factor receptor signaling and estrogen receptor α expression were inhibited, which was associated with apoptosis and autophagy. Delphinidin chloride regulates JAK/STAT3 and MAPKinase signaling. Delphinidin also inhibited the histone acetyltransferase activity of p300/CBP (IC50 was about 30 μM) .

Apoptosis, Epigenetic Reader Domain, VEGFR, Estrogen Receptor/ERR, JAK, EGFR, STAT

Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells, JAK/STAT signaling, Endocrinology/Hormones, Apoptosis, Angiogenesis

475

0.9993

C15H11ClO7

338.7

[Cl-].Oc1cc(O)c2cc(O)c([o+]c2c1)-c1cc(O)c(O)c(O)c1

-20°C

Ice Packs

Natural Product