Deltarasin HCl - CAS 1440898-82-7

Deltarasin is a high affinity PDEδ-KRAS interaction inhibitor. Deltarasin can inhibit KRAS-PDEδ interactions by binding to a hydrophobic pocket on PDEδ, resulting in the impairment of cell growth, KRAS activity, and RAS/RAF signaling in human pancreatic ductal adenocarcinoma cell lines. The anti-cancer cell activity of deltarasin can be enhanced by simultaneously blocking tumor protective" autophagy

Others, PDE, Kras, Ras

Metabolism, MAPK, GPCR/G Protein, Others

1440809

C40H37N5O.xHCl

713.144

[C@H](COC1=CC=C(C=C1)C=2N(CC3=CC=CC=C3)C=4C(N2)=CC=CC4)(N5C(=NC=6C5=CC=CC6)C7=CC=CC=C7)[C@H]8CCNCC8.Cl

-20°C

Ice Packs

Small Compound