Demethyleneberberine chloride - CAS 16705-03-6

Demethyleneberberine chloride, a natural mitochondria-targeted antioxidant, mitigates colitis in mice and suppresses inflammatory responses by blocking the NF-κB pathway and modulating the equilibrium of Th cells. It is also recognized as an AMPK activator for investigating non-alcoholic fatty liver disease (NAFLD) [1] [2] [3].

AMPK, NF-κB

NF-κB, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic

16705-03-6

C19H18ClNO4

359.8

[Cl-].OC=1C=C2C=3C=C4C=CC(OC)=C(OC)C4=C[N+]3CCC2=CC1O

-20°C

Ice Packs

Small Compound