Demethylzeylasteral - CAS 107316-88-1

Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities. It inhibits the invasion of triple-negative breast cancer by blocking the TGF-β signaling pathway, and it can significantly reduce atherosclerosis.

UGT, TGF-beta/Smad, NF-κB, Apoptosis, FAK, Estrogen Receptor/ERR

Endocrinology/Hormones, Tyrosine Kinase/Adaptors, Angiogenesis, Cytoskeletal Signaling, Metabolism, Apoptosis, NF-κB, Stem Cells

107227

>99.99%

C29H36O6

480.59

[H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC(=O)c4c(C=O)c(O)c(O)cc4[C@]3(C)CC[C@@]21C)C(O)=O

-20°C

Ice Packs

Natural Product