α-Dendrotoxin - CAS 74504-53-3

α-Dendrotoxin (α-DTX) is a small molecular peptide neurotoxin isolated from the venom of the African green mamba snake (Dendroaspis angusticeps) . This compound acts as a blocker for KV1.1, KV1.2, KV1.6, and ASIC channels. By inhibiting potassium channels, α-Dendrotoxin reduces the threshold for neuronal action potentials and increases the frequency of these potentials, thereby enhancing neuronal excitability. It is utilized in neurotoxicological research.

Sodium Channel, Potassium Channel

Membrane transporter/Ion channel

74504-53-3

C305H478N98O84S6

7072

-20°C

Ice Packs

Peptide