Deoxycorticosterone acetate - CAS 56-47-3

Deoxycorticosterone acetate (DOCA) is a steroid hormone produced by the adrenal glands, possessing mineralocorticoid activity and serving as a precursor to aldosterone. As an agonist of the mineralocorticoid receptor, DOCA can induce severe kidney damage, including inflammation, fibrosis, glomerular injury, and proteinuria. It is commonly used to establish animal models of chronic kidney injury and hypertension.

Endogenous Metabolite, Glucocorticoid Receptor, Adrenergic Receptor

Neuroscience, GPCR/G Protein, Endocrinology/Hormones, Metabolism

6

>99.99%

C23H32O4

372.5

[H][C@@]12CC[C@H](C(=O)COC(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C

-20°C

Ice Packs

Natural Product