Des-4-fluorobenzyl Mosapride - CAS 152013-26-8

Des-4-fluorobenzyl Mosapride, the main metabolite of mosapride, acts as a gastroprokinetic agent improving upper gastrointestinal (GI) motility by stimulating the serotonin receptor 4 (5-HT4; EC50= 74.2 nM, in guinea pig ileal longitudinal muscle myenteric plexus) . It has been shown to increase colonic motility in dogs, horses, and guinea pigs in vivo. Mosapride, including this metabolite, is utilized in human and veterinary medicine to mitigate post-surgical and Parkinson's-induced constipation.

Others, 5-HT Receptor

Others, Neuroscience, GPCR/G Protein

152013-26-8

C14H20ClN3O3

313.78

CCOc1cc(N)c(Cl)cc1C(=O)NCC1CNCCO1

-20°C

Ice Packs

Small Compound