Deserpidine hydrochloride - CAS 6033-69-8

Deserpidine hydrochloride is the salf form of Deserpidine (free base), which is an antihypertensive drug related to reserpine which occurs naturally in Rauwolfia canescens. Deserpidine is a competitive inhibitor of the angiotensin converting enzyme (ACE) . By competing with angiotensin I for ACE, deserpidine blocks the conversion of angiotensin I to angiotensin II, which is a potent vasoconstrictor. Reduced level of serum angiotensin II causes a decrease in blood pressure. Deserpidine also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex.

Others, Angiotensin-converting Enzyme (ACE)

Metabolism, Others

5956

C32H39ClN2O8

615.12

CCC(CC)C1C2=C(NN=C2C2=CC=CC=C2)OC(N)=C1C#N

-20°C

Ice Packs

Small Compound