(±) -Desisopropylpropranolol - CAS 20862-11-7

(±) -Desisopropylpropranolol (N-Desisopropylpropranolol) is a metabolite of Propranolol. Propranolol acts as a non-selective β-adrenergic receptor (βAR) antagonist with high affinity for both β1AR and β2AR, having Ki values of 1.8 nM and 0.8 nM, respectively. It inhibits the binding of [3H]-DHA to rat brain membrane preparations with an IC50 of 12 nM. Propranolol is used in studies related to hypertension, pheochromocytoma, myocardial infarction, arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.

Drug Metabolite, Adrenergic Receptor

Neuroscience, Metabolism, GPCR/G Protein

20844

C13H15NO2

217.26

OC(COC1=CC=CC=2C=CC=CC12)CN

-20°C

Ice Packs

Small Compound