Desmethoxyyangonin - CAS 15345-89-8

1. Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydromethysticin and Desmethoxy yangonin involves transcription activation, probably through a PXR-independent or PXR-involved indirect mechanism.

NO Synthase, Monoamine Oxidase, JAK, STAT, IκB/IKK, Cytochromes P450

Tyrosine Kinase/Adaptors, JAK/STAT signaling, Chromatin/Epigenetic, Neuroscience, NF-κB, Angiogenesis, Immunology/Inflammation, Stem Cells, Metabolism

15248

0.9961

C14H12O3

228.24

COc1cc(\C=C\c2ccccc2)oc(=O)c1

-20°C

Ice Packs

Natural Product