Desmethyl Bosentan - CAS 253688-61-8

Desmethyl bosentan, an active metabolite of the endothelin receptor antagonist bosentan, activates the pregnane X receptor (PXR) in CV-1 monkey kidney cells expressing the human receptor in a reporter assay at a concentration of 25 μM.

Cytochromes P450, Others, Drug Metabolite

Others, Metabolism

253688-61-8

C26H27N5O6S

537.59

CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1nc(nc(OCCO)c1Oc1ccccc1O)-c1ncccn1

-20°C

Ice Packs

Small Compound