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Desmethyl Erlotinib hydrochloride - CAS 183320-51-6

Desmethyl Erlotinib hydrochloride - CAS 183320-51-6

MF-0094699-01

$50.37 USD
$50.37 USD
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Product Details

  • Bioactivity

    Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for human EGFR and EGFR autophosphorylation in tumor cells.

  • Target

    Drug Metabolite, EGFR

  • Related Pathways

    JAK/STAT signaling, Metabolism, Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    183263

  • Purity

    0.9949

  • Molecular Formula

    C21H21N3O4·HCl

  • Molecular Weight

    415.87

  • SMILES

    Cl.COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCO

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound