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Desmethyl-QCA276 - CAS 2126819-55-2

Desmethyl-QCA276 - CAS 2126819-55-2

MF-0138387-01

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Product Details

  • Bioactivity

    Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1].

  • Target

    Others, Ligands for Target Protein for PROTAC

  • Related Pathways

    Others, PROTAC

  • CAS Number

    2126762

  • Molecular Formula

    C21H17N5OS

  • Molecular Weight

    387.46

  • SMILES

    C(#CC=1SC2=C(C1CC=3C=CC=CC3)COCC4=NN=C(N42)C)C=5C=NNC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC