Desmethylazelastine - CAS 47491-38-3

Desmethylazelastine, the primary active metabolite of Azelastine, undergoes oxidative metabolism via the cytochrome P450 enzyme system, exhibits a 97% protein binding rate, and has an elimination half-life of 54 hours. Azelastine, an orally active, selective, and high-affinity histamine H1-receptor antagonist, is utilized in the research of allergic rhinitis, asthma, diabetic hyperlipidemia, and SARS-CoV-2 [1] [2] [3] [4] [5].

Others, Drug Metabolite

Others, Metabolism

47450

C21H22ClN3O

367.87

Clc1ccc(Cc2nn(C3CCCNCC3)c(=O)c3ccccc23)cc1

-20°C

Ice Packs

Small Compound