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Desmorpholinyl Navitoclax-NH-Me - CAS 2365172-82-1

Desmorpholinyl Navitoclax-NH-Me - CAS 2365172-82-1

MF-0006260-01

$44.38 USD
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Product Details

  • Bioactivity

    Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2].

  • Target

    Bcl-2 Family, Ligands for Target Protein for PROTAC

  • Related Pathways

    Apoptosis, PROTAC

  • CAS Number

    2365172-82-1

  • Purity

    0.9987

  • Molecular Formula

    C44H51ClF3N5O5S3

  • Molecular Weight

    918.55

  • SMILES

    CNCC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(CC2=C(CCC(C)(C)C2)c2ccc(Cl)cc2)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC