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Molfinity

Destruxin B2 - CAS 79386-00-8

Destruxin B2 - CAS 79386-00-8

SKU:MF-0051489

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  • Bioactivity

    Destruxin B2 is a cyclic hexadepsipeptide mycotoxin that has been found in M. anisopliae and has antiviral, insecticidal, and phytotoxic activities.1,2,3 It inhibits secretion of hepatitis B virus surface antigen (HBsAg) by Hep3B cells expressing hepatitis B virus (HBV) DNA (IC50 = 1.3 μM) .1 Destruxin B2 is toxic to Sf9 insect cells in an electric cell-substrate impedance sensing (ECIS) test with a 50% inhibitory concentration (ECIS50) value of 92 μM.4 It is also phytotoxic to B. napus leaves.3

  • Target

    Others, HBV

  • Related Pathways

    Microbiology/Virology, Others

  • CAS Number

    79386-00-8

  • Molecular Formula

    C29H49N5O7

  • Molecular Weight

    579.739

  • SMILES

    [H][C@@]12CCCN1C(=O)[C@@H](CC(C)C)OC(=O)CCNC(=O)[C@H](C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](NC2=O)C(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound